文章来源:《临床神经外科杂志》,,17(03):-.
作者:《加重继发性脑损伤危险因素防治专家共识》专家组
通信作者:费舟(空军医院神经外科)
加重继发性脑损伤的危险因素(SBIF)是指在原发性脑损伤后,诸如颅内压、脑灌注压、体温、血压等指标,若发生异常改变,可引起脑的再次损伤,从而加重继发性脑损伤,这些异常改变的指标也可称之为二次脑损伤因素。重型颅脑损伤后多伴有SBIF,可显著增加致死率和致残率,严重影响患者预后;及早治疗或预防SBIF,对提高颅脑损伤救治水平有重大意义。本文结合数十位国内神经外科、重症、呼吸、循环等专家临床经验和国内外相关文献报道,对SBIF从病因、监测、诊断及治疗等方面进行了系统讨论,形成共识,为SBIF临床防治提供参考。ExpertsConsensusonthemanagementoffactorsofsecondarybraininsultsfollowingtraumaticbraininjuryManagementofFactorsofSecondaryBrainInsultsExpertsGroupAbstract:Intraumaticbraininjury(TBI),thebrainmaybedamagedbyprimaryimpact,butfactorsofsecondarybraininsults(SBIF)followingprimaryimpactsuchasabnormalchangesofintracranialpressure,cerebralperfusionpressure,bodytemperatureandbloodpressureetc,areotherimportantcausesofdamagetothebrain.SevereTBIcoupledwithSBIFisassociatedwithanincreaseinmortalityandmorbidity,andseriouslyaffectstheprognosisofpatients.EarlymanipulationofSBIFisofgreatsignificanceforimprovingout